ALK2/YBL009W Summary

ALK2 BASIC INFORMATION

Standard Name	ALK2 1
Systematic Name	YBL009W
Feature Type	ORF, Verified
Description	Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk1p and to mammalian haspins (1)

GO Annotations	All ALK2 GO evidence and references
	View Computational GO annotations for ALK2
Molecular Function
Manually curated	protein kinase activity (IDA) protein serine/threonine kinase activity (ISS)
Biological Process
Manually curated	meiosis (IEP) mitosis (IEP, IMP) protein amino acid phosphorylation (IDA)
Cellular Component
Manually curated	cellular_component unknown (ND)

Mutant Phenotype	All ALK2 Phenotype details and references
Classical genetics
null	viable
overexpression	cell cycle progression in G2 phase: abnormal cell cycle progression in M phase: arrested cellular morphology: abnormal
Large-scale survey
null	sporulation: normal viable
overexpression	vegetative growth: decreased

Interactions	ALK2 All interactions details and references
	6 total interaction(s) for 6 unique genes/features.
Genetic Interactions	Phenotypic Suppression: 6

Sequence Information

ChrII:207197 to 209227 | |

Last Update

Coordinates: 2004-07-16 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..2031	207197..209227	2004-07-16	1997-01-28

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000105

ALK2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for ALK2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ALK2]

1)	Nespoli A, et al. (2006) Alk1 and Alk2 are two new cell cycle-regulated haspin-like proteins in budding yeast. Cell Cycle 5(13):1464-71

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