TEL12R-YP1 Summary Help

Systematic Name TEL12R-YP1
Feature Type Y'_element
Description Long telomeric Y' element on the right arm of Chromosome XII; more end-proximal of two long telomeric Y' elements; contains an ARS consensus sequence, a region of 36-bp repeats, ORFs YRF1-5/YLR467W and YLR467C-A, and part of ORF YLR466C-B (1, 2, 3 and see Summary Paragraph)
Chromosomal Location
ChrXII:1071654 to 1078177 | ORF Map | GBrowse
sequence information
ChrXII:1071654 to 1078177 | ORF Map | GBrowse
This feature contains embedded feature(s): YRF1-5 | YLR467C-A
This feature is contained within: TEL12R
Last Update Coordinates: 2011-02-03 | Sequence: 2003-09-09
Subfeature details
Most Recent Updates
Coordinates Sequence
Repeat region 4615..5041 1076268..1076694 2011-02-03 2003-09-09
ACS 6434..6444 1078087..1078097 2011-02-03 2003-09-09
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
External Links All Associated Seq | Search all NCBI (Entrez)
Primary SGDIDS000028987

TEL12R-YP1, the more end-proximal of two long Y' (Y'-L) elements on the right arm of chromosome XII, contains an ARS consensus sequence, a region of 36-bp repeats, one verified ORF YRF1-5/YLR467W, part of an uncharacterized ORF YLR466C-B, and one dubious ORF YLR467C-A.

The Y' element is a repetitive sequence found in many but not all subtelomeric regions next to the telomeric repeats, or adjacent X element combinatorial repeats, either as a single copy or tandem repeat of two to four copies (2, 3). Two main types of Y' elements are known, Y'-L and Y'-S, and any particular array will consist of only one type, not a combination of both (1). Y' elements contain helicase-encoding ORFs which are expressed only during meiosis and in telomerase-deficient cells (1). Possible functions include rescue of telomeres when the telomeric repeats are no longer present and a role in telomere maintenance during meiosis (1).

Other features of TEL12R, the right telomeric region of chromosome XII, include an X element core sequence TEL12R-XC, a region of X element combinatorial repeats TEL12R-XR, two stretches of telomeric repeats (TEL12R-TR1, TEL12R-TR2), and an additional Y' element TEL12L-YP2.

Click on the following figure for more details:

telomere map

Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.

Last updated: 2003-11-18 Contact SGD

References cited on this page View Complete Literature Guide for TEL12R-YP1
1) Yamada M, et al.  (1998) Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. J Biol Chem 273(50):33360-6
2) Louis EJ and Haber JE  (1992) The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics 131(3):559-74
3) Pryde FE, et al.  (1997) Chromosome ends: all the same under their caps. Curr Opin Genet Dev 7(6):822-8