SUMMARY PARAGRAPH for TEL08R-YP
TEL08R-Yp, the short Y' (Y'-S) element on the right arm of chromosome VIII, contains an ARS consensus sequence, a region of 36-bp repeats, two uncharacterized ORFs (YHR218W, YHR219W), and two dubious ORFs (YHR218W-A, YHR219C-A).
The Y' element is a repetitive sequence found in many but not all subtelomeric regions next to the telomeric repeats, or adjacent X element combinatorial repeats, either as a single copy or tandem repeat of two to four copies(2, 3). Two main types of Y' elements are known, Y'-L and Y'-S, and any particular array will consist of only one type, not a combination of both (1). Y' elements contain helicase-encoding ORFs which are expressed only during meiosis and in telomerase-deficient cells (1). Possible functions include rescue of telomeres when the telomeric repeats are no longer present and a role in telomere maintenance during meiosis (1).
Other features of TEL08R, the right telomeric region of chromosome VIII, include an X element core sequence TEL08R-XC, a region of X element combinatorial repeats TEL08R-XR, and two stretches of telomeric repeats (TEL08R-TR1, TEL08R-TR2).
Click on the following figure for more details:
Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.
Last updated: 2003-11-18