TEL12L-YP2 Summary Help

Systematic Name TEL12L-YP2
Feature Type Y'_element
Description Short Y' element in the left telomere of Chromosome XII; more centromere-proximal of two short Y' elements; contains an ARS consensus sequence, a region of 36-bp repeats, and two ORFs YLL066C and YLL066W-A (1, 2, 3 and see Summary Paragraph)
Chromosomal Location
ChrXII:11196 to 5724 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
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sequence information
ChrXII:11196 to 5724 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
This feature contains embedded feature(s): YLL066C | YLL066W-A
This feature is contained within: TEL12L
SGD ORF map
Last Update Coordinates: 2003-09-09 | Sequence: 2003-09-09
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
Repeat region 3447..3873 7750..7324 2003-09-09 2003-09-09
ACS 5266..5276 5931..5921 2003-09-09 2003-09-09
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
Resources
External Links All Associated Seq | Search all NCBI (Entrez)
Primary SGDIDS000028917
SUMMARY PARAGRAPH for TEL12L-YP2

TEL12L-YP2, the more centromere-proximal of two short Y' (Y'-S) elements on the left arm of chromosome XII, contains an ARS consensus sequence, a region of 36-bp repeats, one uncharacterized ORF YLL066C, and one dubious ORF YLL066W-A.

The Y' element is a repetitive sequence found in many but not all subtelomeric regions next to the telomeric repeats, or adjacent X element combinatorial repeats, either as a single copy or tandem repeat of two to four copies (2, 3). Two main types of Y' elements are known, Y'-L and Y'-S, and any particular array will consist of only one type, not a combination of both (1). Y' elements contain helicase-encoding ORFs which are expressed only during meiosis and in telomerase-deficient cells (1). Possible functions include rescue of telomeres when the telomeric repeats are no longer present and a role in telomere maintenance during meiosis (1).

Other features of TEL12L, the left telomeric region of chromosome XII, include an X element core sequence TEL12L-XC, a region of X element combinatorial repeats TEL12L-XR, three stretches of telomeric repeats (TEL12L-TR1, TEL12L-TR2, TEL12L-TR3), and an additional short Y' element TEL12L-YP1.

Click on the following figure for more details:

telomere map

Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.

Last updated: 2003-11-18 Contact SGD

References cited on this page View Complete Literature Guide for TEL12L-YP2
1) Yamada M, et al.  (1998) Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. J Biol Chem 273(50):33360-6
2) Louis EJ and Haber JE  (1992) The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics 131(3):559-74
3) Pryde FE, et al.  (1997) Chromosome ends: all the same under their caps. Curr Opin Genet Dev 7(6):822-8