TEL12L-XR Summary Help

Systematic Name TEL12L-XR
Feature Type X_element_combinatorial_repeats
Description Telomeric X element combinatorial repeat on the left arm of Chr XII; contains repeats of the D, C, B and A types, as well as Tbf1p binding sites; formerly called SubTelomeric Repeats (1, 2 and see Summary Paragraph)
Chromosomal Location
ChrXII:11625 to 11359 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
sequence information
ChrXII:11625 to 11359 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
This feature is contained within: TEL12L
SGD ORF map
Last Update Coordinates: 2003-09-09 | Sequence: 2003-09-09
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
Resources
External Links All Associated Seq | Search all NCBI (Entrez)
Primary SGDIDS000028915
SUMMARY PARAGRAPH for TEL12L-XR

TEL12L-XR, the X element combinatorial repeat region on the left arm of chromosome XII, spans 266 bp and contains repeats of the D, C, B and A types, as well as Tbf1p binding sites.

Formerly known as subtelomeric repeats or STRs, X element combinatorial repeats are generally between 250 and 300 bp long and are located between the X element core sequence and the telomeric end (1). X element combinatorial repeats are usually present as a combination of one or more of several types of smaller elements designated D, C, B, or A, with D types being most proximal to the centromere, followed by C types and so on (2). Most X element combinatorial repeat regions contain Tbf1p binding sites, and possible functions include a role in telomerase-independent telomere maintenance via recombination or as a barrier against transcriptional silencing (2).

Other features of TEL12L, the left telomeric region of chromosome XII, include an X element core sequence TEL12L-XC, three regions of telomeric repeats (TEL12L-TR1, TEL12L-TR2, TEL12L-TR3), and two short Y' elements (TEL12L-YP1, TEL12L-YP2).

Click on the following figure for more details:

telomere map

Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.

Last updated: 2003-11-03 Contact SGD

References cited on this page View Complete Literature Guide for TEL12L-XR
1) Louis EJ  (1995) The chromosome ends of Saccharomyces cerevisiae. Yeast 11(16):1553-73
2) Louis EJ, et al.  (1994) The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics. Genetics 136(3):789-802