TEL12L-XC Summary Help

Systematic Name TEL12L-XC
Feature Type X_element_core_sequence
Description Telomeric X element Core sequence on the left arm of Chromosome XII; contains an ARS consensus sequence, an Abf1p binding site consensus sequence, and ORF YLL065W (1, 2 and see Summary Paragraph)
Chromosomal Location
ChrXII:12085 to 11626 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
sequence information
ChrXII:12085 to 11626 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
This feature contains embedded feature(s): YLL065W
This feature is contained within: TEL12L
SGD ORF map
Last Update Coordinates: 2003-09-09 | Sequence: 2003-09-09
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
ACS 39..49 12047..12037 2003-09-09 2003-09-09
Binding site 258..270 11828..11816 2003-09-09 2003-09-09
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
Resources
External Links All Associated Seq | Search all NCBI (Entrez)
Primary SGDIDS000028914
SUMMARY PARAGRAPH for TEL12L-XC

TEL12L-XC, the X element core sequence on the left arm of chromosome XII, spans 459 bp and contains an ARS consensus sequence, an Abf1p binding site consensus sequence, and a dubious ORF YLL065W.

Small conserved elements of ~475 bp, X element core sequences contain ARS consensus sequences and in most cases Abf1p binding sites, and are the only regions shared by all chromosome ends (2, 1). Between the ARS consensus sequence and the Abf1p binding site is a GC-rich region nearly identical to the meiosis-specific regulatory sequence URS1 (1). Possible functions include roles in chromosomal segregation, maintenance of chromosome stability, recombinational sequestering, or as a barrier to transcriptional silencing (1).

Other features of TEL12L, the left telomeric region of chromosome XII, include X element combinatorial repeats TEL12L-XR, three separate stretches of telomeric repeats (TEL12L-TR1, TEL12L-TR2, TEL12L-TR3), and two short Y' elements (TEL12L-YP1 and TEL12L-YP2).

Click on the following figure for more details:

telomere map

Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.

Last updated: 2003-10-31

References cited on this page View Complete Literature Guide for TEL12L-XC
1) Louis EJ  (1995) The chromosome ends of Saccharomyces cerevisiae. Yeast 11(16):1553-73
2) Louis EJ, et al.  (1994) The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics. Genetics 136(3):789-802