SUMMARY PARAGRAPH for TEL10L-XC
TEL10L-XC, the X element core sequence on the left arm of chromosome X, spans 462 bp and contains an ARS consensus sequence and an Abf1p binding site consensus sequence.
Small conserved elements of ~475 bp, X element core sequences contain ARS consensus sequences and in most cases Abf1p binding sites, and are the only regions shared by all chromosome ends (2, 1). Between the ARS consensus sequence and the Abf1p binding site is a GC-rich region nearly identical to the meiosis-specific regulatory sequence URS1 (1). Possible functions include roles in chromosomal segregation, maintenance of chromosome stability, recombinational sequestering, or as a barrier to transcriptional silencing (1).
Other features of TEL10L, the left telomeric region of chromosome X, include an X element combinatorial repeat TEL10L-XR, a long Y' (Y'-L) element TEL10L-YP, and a short terminal stretch of telomeric repeats TEL10L-TR.
Click on the following figure for more details:
Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.
Last updated: 2003-10-31