TEL07L Summary Help

Systematic Name TEL07L
Feature Type telomere
Description Telomeric region on the left arm of Chromosome VII; composed of an X element core sequence, X element combinatorial repeats, and a short terminal stretch of telomeric repeats (1, 2 and see Summary Paragraph)
Chromosomal Location
ChrVII:781 to 1 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -172 cM
sequence information
ChrVII:781 to 1 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
This feature contains embedded feature(s): TEL07L-TR | TEL07L-XC | TEL07L-XR
SGD ORF map
Genetic position: -172 cM
Last Update Coordinates: 2003-09-09 | Sequence: 2003-09-09
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
Resources
External Links All Associated Seq | Search all NCBI (Entrez)
Primary SGDIDS000028887
SUMMARY PARAGRAPH for TEL07L

The chromosome ends of Saccharomyces cerevisiae are complex mosaics of several different types of telomeric and subtelomeric elements known as X element core sequences, X element combinatorial repeats, telomeric repeats, and Y' elements (2). The X element core sequence, a small conserved element of ~475 bp containing an ARS sequence and in most cases an Abf1p binding site, is the only region shared by all chromosome ends (2, 1). The X element combinatorial repeats, formerly known as subtelomeric repeats or STRs, are located between the X element core sequence and the telomeric end and are usually present as a combination of one or more of several types of smaller elements designated D, C, B, or A (2, 1). The telomeric repeat is a G-rich terminal sequence of the form (TG1-3)n that is maintained by telomerase (1). The Y' element is a helicase-encoding repetitive sequence found in many but not all subtelomeric regions next to the telomeric repeats, or adjacent X element combinatorial repeats, either as a single copy or tandem repeat of two to four copies (3, 1, 4). Possible functions of telomeric regions include roles in chromosomal segregation, maintenance of chromosome stability, recombinational sequestering, or as a barrier to transcriptional silencing (2, 1).

TEL07L, the left telomeric region of chromosome VII, is composed of an X element core sequence TEL07L-XC containing an ARS consensus sequence and an Abf1p binding site, X element combinatorial repeats TEL07L-XR of the D, C, B and A types containing Tbf1p binding sites, and a short terminal stretch of telomeric repeats TEL07L-TR.

Click on the following figure for more details:

telomere map

Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.

Last updated: 2003-10-29 Contact SGD

References cited on this page View Complete Literature Guide for TEL07L
1) Louis EJ  (1995) The chromosome ends of Saccharomyces cerevisiae. Yeast 11(16):1553-73
2) Louis EJ, et al.  (1994) The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics. Genetics 136(3):789-802
3) Louis EJ and Haber JE  (1992) The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics 131(3):559-74
4) Yamada M, et al.  (1998) Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. J Biol Chem 273(50):33360-6