SUMMARY PARAGRAPH for TEL05L-YP
TEL05L-Yp, the long Y' (Y'-L) element on the left arm of chromosome V, contains an ARS consensus sequence, a region of 36-bp repeats, four uncharacterized ORFs (YEL075C, YEL076C, YEL076C-A, YEL077C), and two dubious ORFs (YEL075W-A, YEL077W-A).
The Y' element is a repetitive sequence found in many but not all subtelomeric regions next to the telomeric repeats, or adjacent X element combinatorial repeats, either as a single copy or tandem repeat of two to four copies(3, 4). Two main types of Y' elements are known, Y'-L and Y'-S, and any particular array will consist of only one type, not a combination of both (5). Y' elements contain helicase-encoding ORFs which are expressed only during meiosis and in telomerase-deficient cells (5). Possible functions include rescue of telomeres when the telomeric repeats are no longer present and a role in telomere maintenance during meiosis (5).
Other features of TEL05L, the left telomeric region of chromosome V, include an X element core sequence TEL05L-XC.
Click on the following figure for more details:
Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.
Last updated: 2003-11-18