Standard Name	VMA9 1
Systematic Name	YCL005W-A
Alias	CWH36 2 , LDB10
Feature Type	ORF, Verified
Description	Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex; essential for vacuolar acidification; interacts with the V-ATPase assembly factor Vma21p in the ER; involved in V0 biogenesis (1, 3)
Name Description	Vacuolar Membrane Atpase 1

Chromosomal Location	ChrIII:107023 to 107417 | ORF Map | GBrowse

	View Computational GO annotations for VMA9
Molecular Function
Manually curated	ATPase activity, coupled to transmembrane movement of ions (IMP)
Biological Process
Manually curated	cell wall mannoprotein biosynthetic process (IMP) protein complex assembly (IMP, IPI) transmembrane transport (IMP) vacuolar acidification (IMP)
Cellular Component
Manually curated	fungal-type vacuole membrane (IMP) vacuolar proton-transporting V-type ATPase, V0 domain (IMP)

Classical genetics
null	alkaline pH resistance: decreased metal resistance: decreased resistance to calcium dichloride: decreased resistance to cyclosporin A: decreased resistance to Congo Red: decreased resistance to Calcofluor White: decreased resistance to FK506: decreased resistance to selenium(2+): decreased resistance to edelfosine: decreased respiratory metabolism: absent small molecule transport: absent viable
unspecified	resistance to Calcofluor White: decreased
Large-scale survey
null	acid pH resistance: decreased alkaline pH resistance: decreased metal resistance: decreased resistance to edelfosine: decreased resistance to ethanol: decreased resistance to amiodarone: decreased resistance to cyclosporin A: decreased resistance to lovastatin: decreased resistance to cisplatin: decreased small molecule transport: absent transposable element transposition: decreased vegetative growth: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	225 total interaction(s) for 223 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 5 Affinity Capture-Western: 2
Genetic Interactions	Negative Genetic: 164 Positive Genetic: 54
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | CGD Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIII:107023 to 107417 | ORF Map | GBrowse
Last Update	Coordinates: 2006-01-12 | Sequence: 2003-07-29
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..11 107023..107033 2006-01-12 2003-07-29 Intron 12..88 107034..107110 2006-01-12 2003-07-29 CDS 89..169 107111..107191 2006-01-12 2003-07-29 Intron 170..265 107192..107287 2006-01-12 2003-07-29 CDS 266..395 107288..107417 2006-01-12 2003-07-29
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (12 - 88) Intron (170 - 265)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000028508