MAE1/YKL029C Summary Help

Standard Name MAE1 1
Systematic Name YKL029C
Feature Type ORF, Verified
Description Mitochondrial malic enzyme; catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids (1)
Name Description MAlic Enzyme 1
Chromosomal Location
ChrXI:384725 to 382716 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All MAE1 GO evidence and references
  View Computational GO annotations for MAE1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 163 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
149 total interaction(s) for 119 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 78
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Negative Genetic: 44
  • Phenotypic Enhancement: 2
  • Positive Genetic: 20
  • Synthetic Growth Defect: 2
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 669
Molecular Weight (Da) 74,375
Isoelectric Point (pI) 8.19
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:384725 to 382716 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2010 384725..382716 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001512
References cited on this page View Complete Literature Guide for MAE1
1) Boles E, et al.  (1998) Identification and characterization of MAE1, the Saccharomyces cerevisiae structural gene encoding mitochondrial malic enzyme. J Bacteriol 180(11):2875-82