ENS2 Summary Help

Standard Name ENS2 1 (see Nomenclature conflict Note)
Feature Type not in systematic sequence of S288C
Description Mitochondrially-encoded 50 kD subunit of Endo.SceI, a dimeric multi-site-specific endonuclease that introduces double-stranded breaks at a number of well-defined sites on the mitochondrial DNA, inducing homologous recombination (2, 3)
Also known as: RF3 , Endo.SceI
Gene Ontology Annotations All ENS2 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Resources
External Links All Associated Seq | Search all NCBI (Entrez)
Primary SGDIDS000029698

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
SCEINomenclature conflictSceI has been used to refer to three different endonucleases: I-SceI, encoded by SCEI/OMEGA; Endo.SceI, composed of Ssc1p/Yjr045p and the mitochondrially-encoded Ens2p; and PI-SCEI/VDE, the TFP1-derived endonuclease.
VDENomenclature conflictSceI has been used to refer to three different endonucleases: I-SceI, encoded by SCEI/OMEGA; Endo.SceI, composed of Ssc1p/Yjr045p and the mitochondrially-encoded Ens2p; and PI-SCEI/VDE, the TFP1-derived endonuclease.
References cited on this page View Complete Literature Guide for ENS2
1) Nakagawa K, et al.  (1991) A maturase-like subunit of the sequence-specific endonuclease endo.SceI from yeast mitochondria. J Biol Chem 266(3):1977-84
2) Nakagawa K, et al.  (1992) An endonuclease with multiple cutting sites, Endo.SceI, initiates genetic recombination at its cutting site in yeast mitochondria. EMBO J 11(7):2707-15
3) Shibata T, et al.  (1995) Multi-site-specific endonucleases and the initiation of homologous genetic recombination in yeast. Adv Biophys 31:77-91