SUMMARY PARAGRAPH for TEL15R-XC
TEL15R-XC, the X element core sequence on the right arm of chromosome XV, spans 445 bp and contains an ARS consensus sequence, an Abf1p binding site consensus sequence, and an uncharacterized ORF YOR394C-A.
Small conserved elements of ~475 bp, X element core sequences contain ARS consensus sequences and in most cases Abf1p binding sites, and are the only regions shared by all chromosome ends (2, 1). Between the ARS consensus sequence and the Abf1p binding site is a GC-rich region nearly identical to the meiosis-specific regulatory sequence URS1 (1). Possible functions include roles in chromosomal segregation, maintenance of chromosome stability, recombinational sequestering, or as a barrier to transcriptional silencing (1).
Other features of TEL15R, the right telomeric region of chromosome XV, include X element combinatorial repeats TEL15R-XR, a long Y' (Y'-L) element TEL15R-YP, and a very short terminal stretch of telomeric repeats TEL15R-TR.
Click on the following figure for more details:
Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.
Last updated: 2003-11-03