TEL06R Summary Help

Systematic Name TEL06R
Feature Type telomere
Description Telomeric region on the right arm of Chromosome VI; composed of an X element core sequence and a short terminal stretch of telomeric repeats (1, 2 and see Summary Paragraph)
Chromosomal Location
ChrVI:269731 to 270161 | ORF Map | GBrowse
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Genetic position: 73 cM
sequence information
ChrVI:269731 to 270161 | ORF Map | GBrowse
This feature contains embedded feature(s): TEL06R-TR | TEL06R-XC
SGD ORF map
Genetic position: 73 cM
Last Update Coordinates: 2011-02-03 | Sequence: 2003-09-09
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S288C only
S288C vs. other species
Resources
External Links All Associated Seq | Search all NCBI (Entrez)
Primary SGDIDS000028957
SUMMARY PARAGRAPH for TEL06R

The chromosome ends of Saccharomyces cerevisiae are complex mosaics of several different types of telomeric and subtelomeric elements known as X element core sequences, X element combinatorial repeats, telomeric repeats, and Y' elements (2). The X element core sequence, a small conserved element of ~475 bp containing an ARS sequence and in most cases an Abf1p binding site, is the only region shared by all chromosome ends (2, 1). The X element combinatorial repeats, formerly known as subtelomeric repeats or STRs, are located between the X element core sequence and the telomeric end and are usually present as a combination of one or more of several types of smaller elements designated D, C, B, or A (2, 1). The telomeric repeat is a G-rich terminal sequence of the form (TG1-3)n that is maintained by telomerase (1). The Y' element is a helicase-encoding repetitive sequence found in many but not all subtelomeric regions next to the telomeric repeats, or adjacent X element combinatorial repeats, either as a single copy or tandem repeat of two to four copies (3, 1, 4). Possible functions of telomeric regions include roles in chromosomal segregation, maintenance of chromosome stability, recombinational sequestering, or as a barrier to transcriptional silencing (2, 1).

TEL06R, the right telomeric region of chromosome VI, is composed of an X element core sequence TEL06R-XC containing an ARS consensus sequence and an ABf1p binding site, and a short terminal stretch of telomeric repeats TEL06R-TR.

Click on the following figure for more details:

telomere map

Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.

Last updated: 2003-10-29 Contact SGD

References cited on this page View Complete Literature Guide for TEL06R
1) Louis EJ  (1995) The chromosome ends of Saccharomyces cerevisiae. Yeast 11(16):1553-73
2) Louis EJ, et al.  (1994) The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics. Genetics 136(3):789-802
3) Louis EJ and Haber JE  (1992) The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics 131(3):559-74
4) Yamada M, et al.  (1998) Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. J Biol Chem 273(50):33360-6