SUMMARY PARAGRAPH for TEL12L-XC
TEL12L-XC, the X element core sequence on the left arm of chromosome XII, spans 459 bp and contains an ARS consensus sequence, an Abf1p binding site consensus sequence, and a dubious ORF YLL065W.
Small conserved elements of ~475 bp, X element core sequences contain ARS consensus sequences and in most cases Abf1p binding sites, and are the only regions shared by all chromosome ends (2, 1). Between the ARS consensus sequence and the Abf1p binding site is a GC-rich region nearly identical to the meiosis-specific regulatory sequence URS1 (1). Possible functions include roles in chromosomal segregation, maintenance of chromosome stability, recombinational sequestering, or as a barrier to transcriptional silencing (1).
Other features of TEL12L, the left telomeric region of chromosome XII, include X element combinatorial repeats TEL12L-XR, three separate stretches of telomeric repeats (TEL12L-TR1, TEL12L-TR2, TEL12L-TR3), and two short Y' elements (TEL12L-YP1 and TEL12L-YP2).
Click on the following figure for more details:
Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.
Last updated: 2003-10-31