SUMMARY PARAGRAPH for TEL12L-TR1
TEL12L-TR1 is the 75-bp terminal stretch of telomeric repeats on the left arm of chromosome XII. The telomeric repeat is a G-rich terminal sequence of the form (TG1-3)n or more precisely ((TG)1-6TG2-3)n (1). The repeats are maintained by telomerase and there is generally 300(+/-)75 bp of TG1-3 at a given end (1). Telomeric repeats function in completing chromosome replication and protecting the ends from degradation and end-to-end fusions (1).
Other features of TEL12L, the left telomeric region of chromosome XII, include an X element core sequence TEL12L-XC, a region of X element combinatorial repeats TEL01L-XR, and two other internal regions of telomeric repeats (TEL12L-TR2, TEL12L-TR3).
Click on the following figure for more details:
Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.
Last updated: 2003-11-07