SUMMARY PARAGRAPH for TEL08L-YP
TEL08L-Yp, the short Y' (Y'-S) element on the left arm of chromosome VIII, contains an ARS consensus sequence, a region of 36-bp repeats, two uncharacterized ORFs (YHL049C, YHL050C), and one dubious ORF YHL050W-A.
The Y' element is a repetitive sequence found in many but not all subtelomeric regions next to the telomeric repeats, or adjacent X element combinatorial repeats, either as a single copy or tandem repeat of two to four copies(2, 3). Two main types of Y' elements are known, Y'-L and Y'-S, and any particular array will consist of only one type, not a combination of both (1). Y' elements contain helicase-encoding ORFs which are expressed only during meiosis and in telomerase-deficient cells (1). Possible functions include rescue of telomeres when the telomeric repeats are no longer present and a role in telomere maintenance during meiosis (1).
Other features of TEL08L, the left telomeric region of chromosome VIII, include an X element core sequence TEL08L-XC, an X element combinatorial repeat TEL08L-XR, and a short terminal stretch of telomeric repeats TEL08L-TR.
Click on the following figure for more details:
Further information can be found at the website of Dr. Ed Louis, Institute of Genetics, The University of Nottingham.
Last updated: 2003-11-18