COA2/YPL189C-A Summary Help

Standard Name COA2 1
Systematic Name YPL189C-A
Feature Type ORF, Verified
Description Cytochrome oxidase assembly factor; null mutation results in respiratory deficiency with specific loss of cytochrome oxidase activity; functions downstream of assembly factors Mss51p and Coa1p and interacts with assembly factor Shy1p (1, 2)
Name Description Cytochrome Oxidase Assembly 1
Chromosomal Location
ChrXVI:188513 to 188307 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All COA2 GO evidence and references
  View Computational GO annotations for COA2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 64 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
29 total interaction(s) for 17 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 1

Genetic Interactions
  • Dosage Lethality: 2
  • Dosage Rescue: 6
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 5
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 9

Resources
Length (a.a.) 68
Molecular Weight (Da) 7,533
Isoelectric Point (pI) 10.41
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:188513 to 188307 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2003-07-29
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..207 188513..188307 2011-02-03 2003-07-29
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000028527
References cited on this page View Complete Literature Guide for COA2
1) Pierrel F, et al.  (2008) Coa2 is an assembly factor for yeast cytochrome c oxidase biogenesis that facilitates the maturation of Cox1. Mol Cell Biol 28(16):4927-39
2) Kastenmayer JP, et al.  (2006) Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae. Genome Res 16(3):365-73