VMA9/YCL005W-A Summary Help

Standard Name VMA9 1
Systematic Name YCL005W-A
Alias CWH36 2 , LDB10
Feature Type ORF, Verified
Description Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex; essential for vacuolar acidification; interacts with the V-ATPase assembly factor Vma21p in the ER; involved in V0 biogenesis (1, 3)
Name Description Vacuolar Membrane Atpase 1
Chromosomal Location
ChrIII:107023 to 107417 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All VMA9 GO evidence and references
  View Computational GO annotations for VMA9
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
repressible
Resources
227 total interaction(s) for 223 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 5
  • Affinity Capture-Western: 2

Genetic Interactions
  • Negative Genetic: 165
  • Positive Genetic: 55

Resources
Length (a.a.) 73
Molecular Weight (Da) 8,381
Isoelectric Point (pI) 9.65
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIII:107023 to 107417 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2006-01-12 | Sequence: 2003-07-29
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..11 107023..107033 2006-01-12 2003-07-29
Intron 12..88 107034..107110 2006-01-12 2003-07-29
CDS 89..169 107111..107191 2006-01-12 2003-07-29
Intron 170..265 107192..107287 2006-01-12 2003-07-29
CDS 266..395 107288..107417 2006-01-12 2003-07-29
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000028508
References cited on this page View Complete Literature Guide for VMA9
1) Sambade M and Kane PM  (2004) The yeast vacuolar proton-translocating ATPase contains a subunit homologous to the Manduca sexta and bovine e subunits that is essential for function. J Biol Chem 279(17):17361-5
2) Davis-Kaplan SR, et al.  (2004) Genome-wide analysis of iron-dependent growth reveals a novel yeast gene required for vacuolar acidification. J Biol Chem 279(6):4322-9
3) Compton MA, et al.  (2006) Vma9p (subunit e) is an integral membrane V0 subunit of the yeast V-ATPase. J Biol Chem 281(22):15312-9