Standard Name	COA3 1
Systematic Name	YJL062W-A
Alias	RRG10 2 , COX25 3
Feature Type	ORF, Verified
Description	Mitochondrial inner membrane protein that participates in regulation of COX1 translation, Cox1p stabilization, and cytochrome oxidase assembly (1, 2, 3, 4)
Name Description	Cytochrome Oxidase Assembly 1

Chromosomal Location	ChrX:316723 to 316980 | ORF Map | GBrowse

	View Computational GO annotations for COA3
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	mitochondrial respiratory chain complex IV assembly (IMP) negative regulation of mitochondrial translation (IMP)
Cellular Component
Manually curated	integral to mitochondrial inner membrane (IDA) mitochondrial inner membrane (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	cytochrome C oxidase activity: decreased Cox1p accumulation: decreased respiratory growth: decreased respiratory growth: absent viable
Large-scale survey
null	respiratory growth: absent
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	32 total interaction(s) for 16 unique genes/features.
Physical Interactions	Affinity Capture-MS: 8 Affinity Capture-RNA: 2 Affinity Capture-Western: 21
Genetic Interactions	Phenotypic Suppression: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrX:316723 to 316980 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2001-02-26
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..258 316723..316980 2011-02-03 2001-02-26
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000007611