AI4/Q0065 Summary Help

Standard Name AI4
Systematic Name Q0065
Feature Type ORF, Verified
Description Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity (1, 2)
Gene Product Alias I-SceII
Chromosomal Location
ChrMito:13818 to 21935 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All AI4 GO evidence and references
  View Computational GO annotations for AI4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
1 total interaction(s) for 1 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 556
Molecular Weight (Da) 63,311
Isoelectric Point (pI) 10.47
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrMito:13818 to 21935 | ORF Map | GBrowse
This feature contains embedded feature(s): AI1 | AI2 | AI3
This feature is contained within: COX1
This feature is contained within: AI5_ALPHA
SGD ORF map
Last Update Coordinates: 2000-05-19 | Sequence: 2000-05-19
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..169 13818..13986 2000-05-19 2000-05-19
Intron 170..2617 13987..16434 2006-01-12 2006-01-12
CDS 2618..2653 16435..16470 2006-01-12 2006-01-12
Intron 2654..5136 16471..18953 2006-01-12 2006-01-12
CDS 5137..5174 18954..18991 2000-05-19 2000-05-19
Intron 5175..6690 18992..20507 2000-05-19 2000-05-19
CDS 6691..8118 20508..21935 2000-05-19 2000-05-19
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000007264
References cited on this page View Complete Literature Guide for AI4
1) Wernette CM, et al.  (1990) Purification of a site-specific endonuclease, I-Sce II, encoded by intron 4 alpha of the mitochondrial coxI gene of Saccharomyces cerevisiae. J Biol Chem 265(31):18976-82
2) Dujardin G, et al.  (1982) Single base substitution in an intron of oxidase gene compensates splicing defects of the cytochrome b gene. Nature 298(5875):628-32