SUP2/tY(GUA)D Summary

SUP2/tY(GUA)D Summary

Standard Name	SUP2 1 (see Nomenclature conflict Note)
Systematic Name	tY(GUA)D
Feature Type	tRNA
Description	Tyrosine tRNA (tRNA-Tyr), predicted by tRNAscan-SE analysis; can mutate to suppress ochre nonsense mutations (1, 2)

Chromosomal Location	ChrIV:946312 to 946400 \| ORF Map \| GBrowse

Gene Ontology Annotations All SUP2 GO evidence and references


Molecular Function
Manually curated	triplet codon-amino acid adaptor activity (TAS)
Biological Process
Manually curated	translational elongation (NAS)
Cellular Component
Manually curated	cytosol (NAS)

interactions All SUP2 Interaction evidence and references

	1 total interaction(s) for 1 unique genes/features.
Genetic Interactions	Dosage Rescue: 1
Resources	BioGRID

sequence information

ChrIV:946312 to 946400 | |

SGD ORF map

Last Update

Coordinates: 2011-02-03 | Sequence: 2000-05-19

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
Noncoding exon	1..39	946312..946350	2011-02-03	2000-05-19
Intron	40..53	946351..946364	2011-02-03	2000-05-19
Noncoding exon	54..89	946365..946400	2011-02-03	2000-05-19

Retrieve sequences

Analyze Sequence

S288C only	ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes
S288C vs. other species	BLASTN vs. fungi

Resources

External Links	All Associated Seq \| Search all NCBI (Entrez)

Primary SGDID	S000006778

NOMENCLATURE CONFLICT NOTE

Name	Relevance	Description
SUP35	Nomenclature conflict	SUP2 has been used to refer to both SUP35/YDR172W, which encodes a translation release factor, and SUP2/tY(GUA)D, which encodes tRNA-Tyr.

References cited on this page View Complete Literature Guide for SUP2

1)	Gilmore RA, et al. (1971) Amino acid replacements resulting from super-suppression of nonsense mutants of iso-1-cytochrome c from yeast. J Mol Biol 61(1):157-73
2)	Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7