LSR1 Summary

LSR1 Summary

Standard Name	LSR1 (see Nomenclature conflict Note)
Alias	snR20 1
Feature Type	snRNA
Description	U2 spliceosomal RNA (U2 snRNA), component of the spliceosome; pairs with the branchpoint sequence; functionally equivalent to mammalian U2 snRNA; stress-induced pseudouridylations at positions 56 and 93 may contribute to regulation of splicing (2, 3, 4, 5)
Name Description	Large Spliceosomal RNA 2
Gene Product Alias	U2 , U2 snRNA

Chromosomal Location	ChrII:681862 to 680688 \| ORF Map \| GBrowse
	Note: this feature is encoded on the Crick strand.

Gene Ontology Annotations All LSR1 GO evidence and references


Molecular Function
Manually curated	pre-mRNA 5'-splice site binding (IDA) RNA binding (TAS)
Biological Process
Manually curated	mRNA 5'-splice site recognition (IDA) mRNA splicing, via spliceosome (IPI)
Cellular Component
Manually curated	U2 snRNP (TAS)

interactions All LSR1 Interaction evidence and references

	5 total interaction(s) for 5 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 4 Protein-RNA: 1

sequence information

ChrII:681862 to 680688 | |

Note: this feature is encoded on the Crick strand.

SGD ORF map

Last Update

Coordinates: 2011-02-03 | Sequence: 2006-10-04

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
Noncoding exon	1..1175	681862..680688	2011-02-03	2006-10-04

Retrieve sequences

Analyze Sequence

S288C only	ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes
S288C vs. other species	BLASTN vs. fungi

Resources

External Links	All Associated Seq \| Search all NCBI (Entrez)

Primary SGDID	S000006478

NOMENCLATURE CONFLICT NOTE

Name	Relevance	Description
GTS1	Nomenclature conflict	The LSR1 name has been used both for the U2 snRNA encoded by LSR1/snR20 and for GTS1/YGL181W.

References cited on this page View Complete Literature Guide for LSR1

1)	Riedel N, et al. (1986) Small nuclear RNAs from Saccharomyces cerevisiae: unexpected diversity in abundance, size, and molecular complexity. Proc Natl Acad Sci U S A 83(21):8097-101
2)	Ares M Jr (1986) U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs. Cell 47(1):49-59
3)	Guthrie C and Patterson B (1988) Spliceosomal snRNAs. Annu Rev Genet 22:387-419
4)	Pascolo E and Seraphin B (1997) The branchpoint residue is recognized during commitment complex formation before being bulged out of the U2 snRNA-pre-mRNA duplex. Mol Cell Biol 17(7):3469-76
5)	Wu G, et al. (2011) U2 snRNA is inducibly pseudouridylated at novel sites by Pus7p and snR81 RNP. EMBO J 30(1):79-89