SGE1/YPR198W Summary Help

Standard Name SGE1 1
Systematic Name YPR198W
Alias NOR1
Feature Type ORF, Verified
Description Plasma membrane multidrug transporter; member of the major facilitator superfamily; acts as an extrusion permease; partial multicopy suppressor of gal11 mutations (1, 2, 3, 4)
Name Description Suppression of Gal11 Expression 1
Chromosomal Location
ChrXVI:934034 to 935665 | ORF Map | GBrowse
Gbrowse
Genetic position: 84.8 cM
Gene Ontology Annotations All SGE1 GO evidence and references
  View Computational GO annotations for SGE1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Large-scale survey
null
Resources
57 total interaction(s) for 54 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 2
  • PCA: 19

Genetic Interactions
  • Dosage Rescue: 6
  • Negative Genetic: 24

Resources
Expression Summary
histogram
Resources
Length (a.a.) 543
Molecular Weight (Da) 59,425
Isoelectric Point (pI) 8.05
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:934034 to 935665 | ORF Map | GBrowse
SGD ORF map
Genetic position: 84.8 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1632 934034..935665 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000006402
References cited on this page View Complete Literature Guide for SGE1
1) Amakasu H, et al.  (1993) Isolation and characterization of SGE1: a yeast gene that partially suppresses the gal11 mutation in multiple copies. Genetics 134(3):675-83
2) Ehrenhofer-Murray AE, et al.  (1994) The Saccharomyces cerevisiae SGE1 gene product: a novel drug-resistance protein within the major facilitator superfamily. Mol Gen Genet 244(3):287-94
3) Ehrenhofer-Murray AE, et al.  (1998) The Sge1 protein of Saccharomyces cerevisiae is a membrane-associated multidrug transporter. Yeast 14(1):49-65
4) Jacquot C, et al.  (1997) The Saccharomyces cerevisiae MFS superfamily SGE1 gene confers resistance to cationic dyes. Yeast 13(10):891-902