OPT2/YPR194C Summary Help

Standard Name OPT2 1
Systematic Name YPR194C
Feature Type ORF, Verified
Description Oligopeptide transporter; member of the OPT family, with potential orthologs in S. pombe and C. albicans; also plays a role in formation of mature vacuoles (2, 3)
Name Description OligoPeptide Transporter 1
Chromosomal Location
ChrXVI:926937 to 924304 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All OPT2 GO evidence and references
  View Computational GO annotations for OPT2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
21 total interaction(s) for 19 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • PCA: 6
  • Protein-peptide: 2

Genetic Interactions
  • Negative Genetic: 9
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 877
Molecular Weight (Da) 101,260
Isoelectric Point (pI) 7.45
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:926937 to 924304 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2634 926937..924304 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000006398
References cited on this page View Complete Literature Guide for OPT2
1) Wiles AM, et al.  (2006) Nutrient regulation of oligopeptide transport in Saccharomyces cerevisiae. Microbiology 152(Pt 10):3133-45
2) Lubkowitz MA, et al.  (1998) Schizosaccharomyces pombe isp4 encodes a transporter representing a novel family of oligopeptide transporters. Mol Microbiol 28(4):729-41
3) Aouida M, et al.  (2009) Novel role for the Saccharomyces cerevisiae oligopeptide transporter Opt2 in drug detoxification. Biochem Cell Biol 87(4):653-61