PRP4/YPR178W Summary Help

Standard Name PRP4 1
Systematic Name YPR178W
Alias RNA4 2
Feature Type ORF, Verified
Description Splicing factor; component of the U4/U6-U5 snRNP complex (3)
Name Description Pre-mRNA Processing 1
Chromosomal Location
ChrXVI:892332 to 893729 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PRP4 GO evidence and references
  View Computational GO annotations for PRP4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
conditional
Large-scale survey
conditional
null
reduction of function
Resources
420 total interaction(s) for 309 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 114
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 3
  • Co-purification: 4
  • Reconstituted Complex: 1
  • Two-hybrid: 7

Genetic Interactions
  • Dosage Rescue: 4
  • Negative Genetic: 215
  • Phenotypic Enhancement: 15
  • Phenotypic Suppression: 4
  • Positive Genetic: 44
  • Synthetic Lethality: 5
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 465
Molecular Weight (Da) 52,442
Isoelectric Point (pI) 5.33
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:892332 to 893729 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1398 892332..893729 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006382
References cited on this page View Complete Literature Guide for PRP4
1) Vijayraghavan U, et al.  (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16
2) Hartwell LH, et al.  (1970) Identification of ten genes that control ribosome formation in yeast. Mol Gen Genet 109(1):42-56
3) Stevens SW and Abelson J  (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31