Standard Name	NCE102 (see Nomenclature conflict Note)
Systematic Name	YPR149W
Alias	NCE2 1
Feature Type	ORF, Verified
Description	Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs); NCE102 has a paralog, FHN1, that arose from the whole genome duplication (1, 2, 3)
Name Description	NonClassical Export 1

Chromosomal Location	ChrXVI:829918 to 830439 | ORF Map | GBrowse

	View Computational GO annotations for NCE102
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	eisosome assembly (IMP) establishment of protein localization to plasma membrane (IMP) negative regulation of protein phosphorylation (IMP) plasma membrane organization (IMP) protein secretion (IGI, IMP)
Cellular Component
Manually curated	cellular bud membrane (IDA) integral to membrane (ISM) mating projection membrane (IDA) colocalizes_with membrane raft (IDA) plasma membrane (IDA)
High-throughput	cytoplasm (IDA) endoplasmic reticulum (IDA) integral to membrane (ISM) mitochondrion (IDA) plasma membrane (IDA)

Classical genetics
null	plasma membrane morphology: abnormal Pil1-GFP distribution: abnormal
Large-scale survey
null	competitive fitness: decreased dessication resistance: decreased haploproficient hyperosmotic stress resistance: decreased Can1p-GFP distribution: abnormal resistance to amitrole: decreased resistance to cycloheximide: decreased resistance to benzo[a]pyrene: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	37 total interaction(s) for 26 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 4 Co-fractionation: 3 Protein-RNA: 1
Genetic Interactions	Dosage Growth Defect: 1 Negative Genetic: 13 Phenotypic Suppression: 1 Positive Genetic: 9
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Mass Spec | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:829918 to 830439 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..522 829918..830439 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000006353