NCE102/YPR149W Summary Help

Standard Name NCE102 1
Systematic Name YPR149W
Alias NCE2 2
Feature Type ORF, Verified
Description Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs); NCE102 has a paralog, FHN1, that arose from the whole genome duplication (2, 3, 4)
Name Description NonClassical Export 2
Chromosomal Location
ChrXVI:829918 to 830439 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NCE102 GO evidence and references
  View Computational GO annotations for NCE102
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
unspecified
Resources
41 total interaction(s) for 29 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 5
  • Co-fractionation: 3
  • Protein-RNA: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 15
  • Phenotypic Suppression: 1
  • Positive Genetic: 9

Resources
Expression Summary
histogram
Resources
Length (a.a.) 173
Molecular Weight (Da) 18,967
Isoelectric Point (pI) 10.08
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:829918 to 830439 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..522 829918..830439 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006353
References cited on this page View Complete Literature Guide for NCE102
1) Grossmann G, et al.  (2008) Plasma membrane microdomains regulate turnover of transport proteins in yeast. J Cell Biol 183(6):1075-88
2) Cleves AE, et al.  (1996) A new pathway for protein export in Saccharomyces cerevisiae. J Cell Biol 133(5):1017-26
3) Bagnat M, et al.  (2000) Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. Proc Natl Acad Sci U S A 97(7):3254-9
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61