MSS18/YPR134W Summary Help

Standard Name MSS18 1
Systematic Name YPR134W
Feature Type ORF, Verified
Description Nuclear encoded protein needed for splicing of mitochondrial intron; required for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions (1)
Name Description Mitochondrial Splicing System 2
Chromosomal Location
ChrXVI:798051 to 798857 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MSS18 GO evidence and references
  View Computational GO annotations for MSS18
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
118 total interaction(s) for 88 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 1
  • Co-purification: 1

Genetic Interactions
  • Dosage Rescue: 4
  • Negative Genetic: 94
  • Positive Genetic: 12
  • Synthetic Growth Defect: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 268
Molecular Weight (Da) 30,957
Isoelectric Point (pI) 5.34
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:798051 to 798857 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..807 798051..798857 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006338
References cited on this page View Complete Literature Guide for MSS18
1) Seraphin B, et al.  (1988) MSS18, a yeast nuclear gene involved in the splicing of intron aI5 beta of the mitochondrial cox1 transcript. EMBO J 7(5):1455-64
2) Faye G and Simon M  (1983) "Processing of the oxi-3 pre-messenger RNA in yeast." Pp. 433-439 in Mitochondria 1983: Nucleo-Mitochondrial Interactions, edited by Schweyen RJ, Wolf K, Kaudewitz F