Standard Name	NAT3 1
Systematic Name	YPR131C
Alias	NAA20 2 , RAD56 3
Feature Type	ORF, Verified
Description	Catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met (4, 5)
Name Description	N-terminal AcetylTransferase 6

Chromosomal Location	ChrXVI:794498 to 793911 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 84.8 cM

	View Computational GO annotations for NAT3
Molecular Function
Manually curated	peptide alpha-N-acetyltransferase activity (IMP, ISS)
Biological Process
Manually curated	cytoskeleton organization (IGI, IMP) mitochondrion inheritance (IGI, IMP) N-terminal peptidyl-methionine acetylation (IMP)
Cellular Component
Manually curated	NatB complex (IDA)
High-throughput	cytoplasm (IDA)

Classical genetics
null	X ray resistance: increased actin cytoskeleton morphology: abnormal bud neck morphology: abnormal cellular morphology: abnormal chromosome/plasmid maintenance: abnormal growth in exponential phase: decreased rate heat sensitivity: increased hyperosmotic stress resistance: decreased ionic stress resistance: decreased mating efficiency: decreased mitochondrial distribution: abnormal carboxypeptidase Y (CPY) activity: increased Zps1p accumulation: increased Ura1p accumulation: decreased Pre1p modification: absent Rps21ap modification: absent Act1p modification: absent iso-1-cytochrome c modification: absent Tfs1p modification: absent Swc7p modification: absent Rnr4p modification: absent resistance to methyl methanesulfonate: decreased resistance to 4-nitroquinoline N-oxide: decreased resistance to ethidium bromide: decreased resistance to hydroxyurea: decreased resistance to calcium dichloride: decreased resistance to benomyl: decreased resistance to thiabendazole: decreased resistance to bleomycin: decreased resistance to ethyl methanesulfonate: decreased resistance to camptothecin: decreased resistance to caffeine: decreased resistance to myriocin: decreased respiratory growth: absent respiratory growth: decreased toxin resistance: decreased vacuolar distribution: abnormal vegetative growth: decreased viable
reduction of function	X ray resistance: decreased resistance to methyl methanesulfonate: decreased spore germination: decreased
Large-scale survey
null	acid pH resistance: decreased budding pattern: abnormal cell cycle progression in G1 phase: increased duration cell shape: abnormal glycogen accumulation: increased competitive fitness: decreased dessication resistance: decreased endocytosis: decreased fermentative growth: decreased rate haploinsufficient heat sensitivity: increased resistance to hygromycin B: decreased resistance to boric acid: decreased resistance to caffeine: decreased resistance to hydroxyurea: decreased resistance to camptothecin: decreased resistance to ethanol: decreased resistance to CTBT: decreased resistance to methyl methanesulfonate: decreased resistance to oleate: decreased resistance to glycolaldehyde: decreased resistance to doxorubicin: decreased stress resistance: increased telomere length: increased vacuolar morphology: abnormal vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	23 total interaction(s) for 17 unique genes/features.
Physical Interactions	Affinity Capture-MS: 11 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Biochemical Activity: 1
Genetic Interactions	Phenotypic Enhancement: 1 Synthetic Growth Defect: 1 Synthetic Lethality: 5 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:794498 to 793911 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 84.8 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 2003-05-23
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..588 794498..793911 2011-02-03 2003-05-23
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000006335