RPC40/YPR110C Summary

RPC40 BASIC INFORMATION

Standard Name	RPC40 1, 2, 3
Systematic Name	YPR110C
Alias	RPC5
Feature Type	ORF, Verified
Description	RNA polymerase subunit AC40, common to RNA polymerase I and III (3, 4)
Name Description	RNA Polymerase C
Gene Product Alias	AC40 3

GO Annotations	All RPC40 GO evidence and references
	View Computational GO annotations for RPC40
Molecular Function
Manually curated	contributes_to DNA-directed RNA polymerase activity (IDA) DNA-directed RNA polymerase activity (TAS)
Biological Process
Manually curated	transcription from RNA polymerase I promoter (TAS) transcription from RNA polymerase III promoter (TAS)
Cellular Component
Manually curated	DNA-directed RNA polymerase I complex (IDA, TAS) DNA-directed RNA polymerase III complex (TAS)

Mutant Phenotype	All RPC40 Phenotype details and references
Classical genetics
conditional	cold sensitivity: increased heat sensitivity: increased RNA polymerase I (A) accumulation: decreased
null	inviable
Large-scale survey
null	inviable

Interactions	RPC40 All interactions details and references
	265 total interaction(s) for 150 unique genes/features.
Physical Interactions	Affinity Capture-MS: 183 Affinity Capture-Western: 3 PCA: 3 Two-hybrid: 6
Genetic Interactions	Dosage Rescue: 4 Phenotypic Enhancement: 51 Phenotypic Suppression: 12 Synthetic Lethality: 3

Sequence Information

ChrXVI:746833 to 745826 | |

Note: this feature is encoded on the Crick strand.

Genetic position: 72 cM

Last Update

Coordinates: 2004-07-21 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1008	746833..745826	2004-07-21	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000006314

RPC40 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for RPC40

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RPC40]

1)	Mann, C. and Treich, I. (1989) Personal Communication, Mortimer Map Edition 10
2)	Johnston, L. (1992) Personal Communication, Mortimer Map Edition 11
3)	Mann C, et al. (1987) RPC40, a unique gene for a subunit shared between yeast RNA polymerases A and C. Cell 48(4):627-37
4)	Lalo D, et al. (1993) Interactions between three common subunits of yeast RNA polymerases I and III. Proc Natl Acad Sci U S A 90(12):5524-8

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