RPN7/YPR108W Summary Help

Standard Name RPN7 1
Systematic Name YPR108W
Feature Type ORF, Verified
Description Essential non-ATPase regulatory subunit of the 26S proteasome; similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits (2)
Name Description Regulatory Particle Non-ATPase 1
Chromosomal Location
ChrXVI:742454 to 743743 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RPN7 GO evidence and references
  View Computational GO annotations for RPN7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Classical genetics
conditional
null
Large-scale survey
null
reduction of function
Resources
188 total interaction(s) for 56 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 107
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 29
  • Co-purification: 3
  • Reconstituted Complex: 4
  • Two-hybrid: 8

Genetic Interactions
  • Negative Genetic: 22
  • Positive Genetic: 10
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 429
Molecular Weight (Da) 48,958
Isoelectric Point (pI) 5
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:742454 to 743743 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1290 742454..743743 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006312
References cited on this page View Complete Literature Guide for RPN7
1) Finley D, et al.  (1998) Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci 23(7):244-5
2) Glickman MH, et al.  (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62