Standard Name	RDS3 1
Systematic Name	YPR094W
Feature Type	ORF, Verified
Description	Component of the SF3b subcomplex of the U2 snRNP, zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance (1, 2, 3)
Name Description	Regulator of Drug Sensitivity 1

Chromosomal Location	ChrXVI:720637 to 720960 | ORF Map | GBrowse

	View Computational GO annotations for RDS3
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	mRNA splicing, via spliceosome (IGI, IMP, IPI) response to xenobiotic stimulus (IMP) spliceosomal complex assembly (IDA, IMP)
Cellular Component
Manually curated	U2 snRNP (IDA)

Classical genetics
null	viable
Large-scale survey
null	inviable resistance to rhodamine 6-G: normal resistance to cycloheximide: decreased resistance to 4-nitroquinoline N-oxide: normal resistance to oligomycin: normal resistance to chloramphenicol: normal resistance to ketoconazole: decreased toxin resistance: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	17 total interaction(s) for 10 unique genes/features.
Physical Interactions	Affinity Capture-MS: 15 Affinity Capture-RNA: 1
Genetic Interactions	Synthetic Growth Defect: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:720637 to 720960 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..324 720637..720960 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000006298