ASR1/YPR093C Summary Help

Standard Name ASR1 1
Systematic Name YPR093C
Feature Type ORF, Verified
Description Ubiquitin ligase that modifies and regulates RNA Pol II; involved in a putative alcohol-responsive signaling pathway; accumulates in the nucleus under alcohol stress; contains a Ring/PHD finger domain similar to the mammalian rA9 protein (1, 2)
Name Description Alcohol Sensitive Ring/PHD finger 1
Chromosomal Location
ChrXVI:720424 to 719558 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ASR1 GO evidence and references
  View Computational GO annotations for ASR1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
88 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 53
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 6
  • Biochemical Activity: 3
  • Co-purification: 1
  • Far Western: 1
  • Protein-peptide: 5
  • Reconstituted Complex: 8
  • Two-hybrid: 4

Genetic Interactions
  • Negative Genetic: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 288
Molecular Weight (Da) 33,346
Isoelectric Point (pI) 5.94
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:720424 to 719558 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2003-09-22
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..867 720424..719558 2011-02-03 2003-09-22
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006297
References cited on this page View Complete Literature Guide for ASR1
1) Betz C, et al.  (2004) Asr1p, a novel yeast ring/PHD finger protein, signals alcohol stress to the nucleus. J Biol Chem 279(27):28174-81
2) Daulny A, et al.  (2008) Modulation of RNA polymerase II subunit composition by ubiquitylation. Proc Natl Acad Sci U S A 105(50):19649-54