Standard Name	MAK3
Systematic Name	YPR051W
Alias	NAA30 1
Feature Type	ORF, Verified
Description	Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus (2, 3)
Name Description	MAintenance of Killer 4

Chromosomal Location	ChrXVI:664960 to 665490 | ORF Map | GBrowse
	Genetic position: 34 cM

	View Computational GO annotations for MAK3
Molecular Function
Manually curated	peptide alpha-N-acetyltransferase activity (IMP)
Biological Process
Manually curated	N-terminal protein amino acid acetylation (IMP)
Cellular Component
Manually curated	NatC complex (IDA)

Classical genetics
null	plasma membrane morphology: abnormal Trm1p-II-GFP distribution: abnormal Imh1p-GFP distribution: abnormal Rps24ap modification: decreased Pup2p modification: absent iso-1-cytochrome c modification: absent viable
Large-scale survey
null	anaerobic growth: decreased competitive fitness: decreased dessication resistance: decreased heat sensitivity: increased hyperosmotic stress resistance: decreased resistance to benzo[a]pyrene: increased resistance to camptothecin: increased resistance to cycloheximide: increased resistance to fenpropimorph: increased resistance to fluconazole: increased resistance to methyl methanesulfonate: increased resistance to arsenite(3-): decreased resistance to neothyonidioside: decreased resistance to bleomycin: decreased resistance to hydroxyurea: decreased resistance to L-canavanine: increased resistance to hygromycin B: decreased stress resistance: increased telomere length: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	82 total interaction(s) for 66 unique genes/features.
Physical Interactions	Affinity Capture-MS: 7 Affinity Capture-RNA: 2 Biochemical Activity: 1 Co-fractionation: 2 Two-hybrid: 3
Genetic Interactions	Negative Genetic: 39 Phenotypic Enhancement: 2 Phenotypic Suppression: 1 Positive Genetic: 5 Synthetic Growth Defect: 17 Synthetic Lethality: 2 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:664960 to 665490 | ORF Map | GBrowse
	Genetic position: 34 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..531 664960..665490 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000006255