Standard Name	NTO1 1, 2
Systematic Name	YPR031W
Feature Type	ORF, Verified
Description	Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3 (3, 4)
Name Description	NuA Three Orf

Chromosomal Location	ChrXVI:631515 to 633761 | ORF Map | GBrowse

	View Computational GO annotations for NTO1
Molecular Function
Manually curated	histone acetyltransferase activity (IPI) methylated histone residue binding (IDA)
Biological Process
Manually curated	histone acetylation (IPI)
Cellular Component
Manually curated	NuA3 histone acetyltransferase complex (IDA)
High-throughput	cytoplasm (IDA) nucleus (IDA)

Large-scale survey
null	anaerobic growth: decreased competitive fitness: increased resistance to caffeine: decreased resistance to tunicamycin: increased resistance to cycloheximide: increased resistance to camptothecin: increased resistance to bleomycin: increased resistance to cycloheximide: decreased resistance to neomycin: decreased resistance to methyl methanesulfonate: decreased resistance to hydroxyurea: decreased starvation resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	86 total interaction(s) for 67 unique genes/features.
Physical Interactions	Affinity Capture-MS: 13 Affinity Capture-Western: 2
Genetic Interactions	Negative Genetic: 54 Phenotypic Enhancement: 6 Positive Genetic: 6 Synthetic Growth Defect: 1 Synthetic Lethality: 1 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:631515 to 633761 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2247 631515..633761 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000006235