CCL1/YPR025C Summary

CCL1 BASIC INFORMATION

Standard Name	CCL1 1
Systematic Name	YPR025C
Feature Type	ORF, Verified
Description	Cyclin associated with protein kinase Kin28p, which is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters (1, 2)

GO Annotations	All CCL1 GO evidence and references
	View Computational GO annotations for CCL1
Molecular Function
Manually curated	cyclin-dependent protein kinase regulator activity (TAS) general RNA polymerase II transcription factor activity (TAS)
Biological Process
Manually curated	negative regulation of transcription from RNA polymerase II promoter, mitotic (TAS) transcription initiation from RNA polymerase II promoter (TAS)
Cellular Component
Manually curated	holo TFIIH complex (IDA) TFIIK complex (IDA)
High-throughput	mitochondrion (IDA)

Mutant Phenotype	All CCL1 Phenotype details and references
Large-scale survey
null	inviable

Interactions	CCL1 All interactions details and references
	48 total interaction(s) for 28 unique genes/features.
Physical Interactions	Affinity Capture-MS: 21 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Co-purification: 5 Reconstituted Complex: 2 Two-hybrid: 6
Genetic Interactions	Dosage Rescue: 1 Phenotypic Enhancement: 2 Phenotypic Suppression: 7 Synthetic Lethality: 2

Sequence Information

ChrXVI:614555 to 613374 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-21 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1182	614555..613374	2004-07-21	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000006229

CCL1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for CCL1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CCL1]

1)	Valay JG, et al. (1993) The kin28 protein kinase is associated with a cyclin in Saccharomyces cerevisiae. J Mol Biol 234(2):307-10
2)	Rodriguez CR, et al. (2000) Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. Mol Cell Biol 20(1):104-12

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