HSP32/YPL280W Summary Help

Standard Name HSP32 1
Systematic Name YPL280W
Feature Type ORF, Verified
Description Possible chaperone and cysteine protease; required for transcriptional reprogramming during the diauxic shift and for survival in stationary phase; similar to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease and cancer (1, 2)
Name Description Heat-Shock Protein 1
Chromosomal Location
ChrXVI:11887 to 12600 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All HSP32 GO evidence and references
  View Computational GO annotations for HSP32
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 6 genes
Resources
Classical genetics
null
Resources
2 total interaction(s) for 2 unique genes/features.
Physical Interactions
  • Two-hybrid: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 237
Molecular Weight (Da) 25,940
Isoelectric Point (pI) 7.71
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:11887 to 12600 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..714 11887..12600 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006201
References cited on this page View Complete Literature Guide for HSP32
1) Wilson MA, et al.  (2004) The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: A member of the DJ-1/ThiJ/PfpI superfamily. Proc Natl Acad Sci U S A 101(6):1531-6
2) Miller-Fleming L, et al.  (2014) Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phase. Proc Natl Acad Sci U S A 111(19):7012-7