KAR9/YPL269W Summary

KAR9 BASIC INFORMATION

Standard Name	KAR9 1
Systematic Name	YPL269W
Feature Type	ORF, Verified
Description	Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules, localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase (1, 2)
Name Description	KARyogamy 1

GO Annotations	All KAR9 GO evidence and references
	View Computational GO annotations for KAR9
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	nuclear migration along microtubule (IMP)
Cellular Component
Manually curated	cell cortex (IDA) mating projection tip (IDA)

Mutant Phenotype	All KAR9 Phenotype details and references
Classical genetics
reduction of function	cytoskeleton morphology: abnormal nuclear fusion during mating: abnormal spindle morphology: abnormal
Large-scale survey
null	competitive fitness: decreased resistance to benomyl: decreased viable

Interactions	KAR9 All interactions details and references
	177 total interaction(s) for 85 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Affinity Capture-Western: 14 Biochemical Activity: 2 Co-fractionation: 1 Co-localization: 1 Reconstituted Complex: 3 Two-hybrid: 24
Genetic Interactions	Phenotypic Enhancement: 24 Phenotypic Suppression: 4 Synthetic Growth Defect: 46 Synthetic Lethality: 57

Sequence Information

ChrXVI:33013 to 34947 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1935	33013..34947	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000006190

KAR9 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for KAR9

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for KAR9]

1)	Miller RK and Rose MD (1998) Kar9p is a novel cortical protein required for cytoplasmic microtubule orientation in yeast. J Cell Biol 140(2):377-90
2)	Miller RK, et al. (1999) The cortical localization of the microtubule orientation protein, Kar9p, is dependent upon actin and proteins required for polarization. J Cell Biol 144(5):963-75

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