APM1/YPL259C Summary Help

Standard Name APM1 1
Systematic Name YPL259C
Alias YAP54 1
Feature Type ORF, Verified
Description Mu1-like medium subunit of the AP-1 complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; the AP-1 complex is the clathrin-associated protein complex (1, 2)
Name Description clathrin Adaptor Protein complex Medium chain 1
Chromosomal Location
ChrXVI:52671 to 51244 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All APM1 GO evidence and references
  View Computational GO annotations for APM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
114 total interaction(s) for 78 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 47
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 6
  • PCA: 1
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 39
  • Phenotypic Enhancement: 3
  • Phenotypic Suppression: 1
  • Positive Genetic: 1
  • Synthetic Growth Defect: 10
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 475
Molecular Weight (Da) 53,873
Isoelectric Point (pI) 9.05
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:52671 to 51244 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1428 52671..51244 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006180
References cited on this page View Complete Literature Guide for APM1
1) Nakayama Y, et al.  (1991) The medium chains of the mammalian clathrin-associated proteins have a homolog in yeast. Eur J Biochem 202(2):569-74
2) Stepp JD, et al.  (1995) A late Golgi sorting function for Saccharomyces cerevisiae Apm1p, but not for Apm2p, a second yeast clathrin AP medium chain-related protein. Mol Biol Cell 6(1):41-58