BBP1/YPL255W Summary

BBP1 BASIC INFORMATION

Standard Name	BBP1
Systematic Name	YPL255W
Feature Type	ORF, Verified
Description	Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p (1, 2)
Name Description	Bfr1p Binding Protein 3

GO Annotations	All BBP1 GO evidence and references
	View Computational GO annotations for BBP1
Molecular Function
Manually curated	structural constituent of cytoskeleton (IPI)
Biological Process
Manually curated	microtubule nucleation (IPI) spindle pole body duplication in nuclear envelope (IMP)
Cellular Component
Manually curated	spindle pole body (IDA)

Mutant Phenotype	All BBP1 Phenotype details and references
Classical genetics
overexpression	budding index: abnormal cell cycle progression: abnormal cell cycle progression in G2 phase: abnormal
Large-scale survey
null	inviable
overexpression	inviable

Interactions	BBP1 All interactions details and references
	34 total interaction(s) for 23 unique genes/features.
Physical Interactions	Affinity Capture-Western: 3 Biochemical Activity: 2 Co-purification: 1 Protein-peptide: 1 Reconstituted Complex: 3 Two-hybrid: 14
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 4 Synthetic Growth Defect: 3 Synthetic Lethality: 1 Synthetic Rescue: 1

Sequence Information

ChrXVI:67725 to 68882 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1158	67725..68882	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000006176

BBP1 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for BBP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BBP1]

1)	Schramm C, et al. (2000) The Bbp1p-Mps2p complex connects the SPB to the nuclear envelope and is essential for SPB duplication. EMBO J 19(3):421-33
2)	Park CJ, et al. (2004) Requirement for Bbp1p in the proper mitotic functions of Cdc5p in Saccharomyces cerevisiae. Mol Biol Cell 15(4):1711-23
3)	Xue Z, et al. (1996) Yeast mutants that produce a novel type of ascus containing asci instead of spores. Genetics 144(3):979-89

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