SUI3/YPL237W Summary Help

Standard Name SUI3 1
Systematic Name YPL237W
Feature Type ORF, Verified
Description Beta subunit of the translation initiation factor eIF2; involved in the identification of the start codon; proposed to be involved in mRNA binding (2)
Name Description SUppressor of Initiator codon 1
Chromosomal Location
ChrXVI:100496 to 101353 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SUI3 GO evidence and references
  View Computational GO annotations for SUI3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 7 genes
Resources
Classical genetics
conditional
null
Large-scale survey
null
overexpression
Resources
125 total interaction(s) for 51 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 51
  • Affinity Capture-RNA: 5
  • Affinity Capture-Western: 28
  • Co-fractionation: 1
  • Far Western: 1
  • Reconstituted Complex: 16
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Dosage Rescue: 2
  • Negative Genetic: 4
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 4
  • Synthetic Growth Defect: 3
  • Synthetic Rescue: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 285
Molecular Weight (Da) 31,574
Isoelectric Point (pI) 10.27
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:100496 to 101353 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..858 100496..101353 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006158
References cited on this page View Complete Literature Guide for SUI3
1) Donahue TF, et al.  (1988) Mutations at a Zn(II) finger motif in the yeast eIF-2 beta gene alter ribosomal start-site selection during the scanning process. Cell 54(5):621-32
2) Laurino JP, et al.  (1999) The beta subunit of eukaryotic translation initiation factor 2 binds mRNA through the lysine repeats and a region comprising the C2-C2 motif. Mol Cell Biol 19(1):173-81