Standard Name	SSO1
Systematic Name	YPL232W
Feature Type	ORF, Verified
Description	Plasma membrane t-SNARE; involved in fusion of secretory vesicles at the plasma membrane and in vesicle fusion during sporulation; forms a complex with Sec9p that binds v-SNARE Snc2p; syntaxin homolog; functionally redundant with Sso2p; SSO1 has a paralog, SSO2, that arose from the whole genome duplication (1, 2, 3, 4, 5)

Chromosomal Location	ChrXVI:107275 to 108147 | ORF Map | GBrowse

	View Computational GO annotations for SSO1
Molecular Function
Manually curated	phosphatidic acid binding (IDA) phosphatidylinositol-3,4-bisphosphate binding (IDA) phosphatidylinositol-3,5-bisphosphate binding (IDA) phosphatidylinositol-4,5-bisphosphate binding (IDA) SNAP receptor activity (IDA, IPI)
Biological Process
Manually curated	ascospore formation (IMP) ascospore-type prospore assembly (IGI, IMP) vesicle fusion (IDA)
Cellular Component
Manually curated	fungal-type vacuole membrane (IDA) plasma membrane (IDA) prospore membrane (IDA) SNARE complex (IDA)
High-throughput	plasma membrane (IDA)

Classical genetics
null	Acb1p secretion: absent sporulation efficiency: decreased viable
reduction of function	sporulation efficiency: decreased
Large-scale survey
null	chronological lifespan: decreased competitive fitness: decreased filamentous growth: increased haploinsufficient resistance to neothyonidioside: decreased sporulation: absent sporulation efficiency: decreased viable
overexpression	filamentous growth: increased vegetative growth: decreased rate vegetative growth: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	152 total interaction(s) for 70 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Affinity Capture-RNA: 2 Affinity Capture-Western: 33 Biochemical Activity: 3 Co-crystal Structure: 2 Co-fractionation: 1 FRET: 3 PCA: 3 Reconstituted Complex: 22 Two-hybrid: 33
Genetic Interactions	Dosage Growth Defect: 3 Dosage Lethality: 5 Dosage Rescue: 16 Negative Genetic: 11 Phenotypic Enhancement: 2 Phenotypic Suppression: 2 Synthetic Growth Defect: 2 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 1 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:107275 to 108147 | ORF Map | GBrowse
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..873 107275..108147 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000006153