NIP7/YPL211W Summary

NIP7 BASIC INFORMATION

Standard Name	NIP7
Systematic Name	YPL211W
Feature Type	ORF, Verified
Description	Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p (1, 2, 3)
Name Description	Nuclear ImPort

GO Annotations	All NIP7 GO evidence and references
	View Computational GO annotations for NIP7
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	ribosomal large subunit assembly (TAS) ribosomal large subunit biogenesis (IPI) rRNA processing (TAS)
Cellular Component
Manually curated	cytosolic large ribosomal subunit (TAS) nucleolus (TAS) preribosome, large subunit precursor (IDA)
High-throughput	preribosome, large subunit precursor (IDA)

Mutant Phenotype	All NIP7 Phenotype details and references
Large-scale survey
null	inviable
repressible	mitochondrial morphology: abnormal

Interactions	NIP7 All interactions details and references
	133 total interaction(s) for 92 unique genes/features.
Physical Interactions	Affinity Capture-MS: 83 Affinity Capture-RNA: 1 Affinity Capture-Western: 5 PCA: 1 Reconstituted Complex: 1 Two-hybrid: 7
Genetic Interactions	Synthetic Growth Defect: 2 Synthetic Lethality: 33

Sequence Information

ChrXVI:153494 to 154039 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..546	153494..154039	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000006132

NIP7 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for NIP7

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NIP7]

1)	Zanchin NI and Goldfarb DS (1999) Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43p. Mol Cell Biol 19(2):1518-25
2)	Zanchin NI, et al. (1997) Saccharomyces cerevisiae Nip7p is required for efficient 60S ribosome subunit biogenesis. Mol Cell Biol 17(9):5001-15
3)	Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27

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