HRR25/YPL204W Summary Help

HRR25 BASIC INFORMATION

Standard Name HRR25
Systematic Name YPL204W
Alias KTI14 1 , 2
Feature Type ORF, Verified
Description Protein kinase involved in regulating diverse events including vesicular trafficking, DNA repair, and chromosome segregation; binds the CTD of RNA pol II; homolog of mammalian casein kinase 1delta (CK1delta) (3, 4)
GO Annotations All HRR25 GO evidence and references
    View Computational GO annotations for HRR25
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All HRR25 Phenotype details and references
Classical genetics
null
reduction of function
repressible
unspecified
Large-scale survey
conditional
null
repressible
Interactions HRR25 All interactions details and references
173 total interaction(s) for 126 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 122
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 7
  • Biochemical Activity: 23
  • Co-fractionation: 1
  • PCA: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 6
Genetic Interactions
  • Dosage Growth Defect: 2
  • Dosage Lethality: 2
  • Phenotypic Enhancement: 2
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 3
Sequence Information
ChrXVI:164275 to 165759 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1485 164275..165759 1996-07-31 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000006125

HRR25 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for HRR25

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for HRR25]

1) Butler AR, et al.  (1994) Two Saccharomyces cerevisiae genes which control sensitivity to G1 arrest induced by Kluyveromyces lactis toxin. Mol Cell Biol 14(9):6306-16
2) Mehlgarten C and Schaffrath R  (2003) Mutant casein kinase I (Hrr25p/Kti14p) abrogates the G1 cell cycle arrest induced by Kluyveromyces lactiszymocin in budding yeast. Mol Genet Genomics 269(2):188-96
3) Milne DM, et al.  (2001) Catalytic activity of protein kinase CK1 delta (casein kinase 1delta) is essential for its normal subcellular localization. Exp Cell Res 263(1):43-54
4) Phatnani HP, et al.  (2004) Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome. Biochemistry 43(50):15702-19