GUP2/YPL189W Summary Help

Standard Name GUP2 1
Systematic Name YPL189W
Feature Type ORF, Verified
Description Probable membrane protein; possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; GUP2 has a paralog, GUP1, that arose from the whole genome duplication (1, 2, 3)
Name Description Glycerol UPtake 1
Chromosomal Location
ChrXVI:189154 to 190983 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All GUP2 GO evidence and references
  View Computational GO annotations for GUP2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Large-scale survey
null
overexpression
repressible
Resources
32 total interaction(s) for 32 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • PCA: 8

Genetic Interactions
  • Negative Genetic: 15
  • Phenotypic Enhancement: 2
  • Positive Genetic: 4
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 609
Molecular Weight (Da) 71,288
Isoelectric Point (pI) 10.38
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:189154 to 190983 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1830 189154..190983 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000006110
References cited on this page View Complete Literature Guide for GUP2
1) Holst B, et al.  (2000) GUP1 and its close homologue GUP2, encoding multimembrane-spanning proteins involved in active glycerol uptake in Saccharomyces cerevisiae. Mol Microbiol 37(1):108-24
2) Hofmann K  (2000) A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling. Trends Biochem Sci 25(3):111-2
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61