OYE3/YPL171C Summary Help

Standard Name OYE3 1
Systematic Name YPL171C
Alias ZRG6 2
Feature Type ORF, Verified
Description Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN); homologous to Oye2p with different ligand binding and catalytic properties; has potential roles in oxidative stress response and programmed cell death (1, 3, 4, 5, 6)
Name Description Old Yellow Enzyme 1
Gene Product Alias Old Yellow Enzyme
Chromosomal Location
ChrXVI:227371 to 226169 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All OYE3 GO evidence and references
  View Computational GO annotations for OYE3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 12 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
56 total interaction(s) for 43 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Protein-peptide: 5
  • Reconstituted Complex: 3

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 39
  • Phenotypic Suppression: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 400
Molecular Weight (Da) 44,920
Isoelectric Point (pI) 5.4
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:227371 to 226169 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1203 227371..226169 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006092
References cited on this page View Complete Literature Guide for OYE3
1) Niino YS, et al.  (1995) A new old yellow enzyme of Saccharomyces cerevisiae. J Biol Chem 270(5):1983-91
2) Yuan DS  (2000) Zinc-regulated genes in Saccharomyces cerevisiae revealed by transposon tagging. Genetics 156(1):45-58
3) Stott K, et al.  (1993) Old Yellow Enzyme. The discovery of multiple isozymes and a family of related proteins. J Biol Chem 268(9):6097-106
4) Brown BJ, et al.  (2002) The role of glutamine 114 in old yellow enzyme. J Biol Chem 277(3):2138-45
5) Trotter EW, et al.  (2006) Old yellow enzymes protect against acrolein toxicity in the yeast Saccharomyces cerevisiae. Appl Environ Microbiol 72(7):4885-92
6) Odat O, et al.  (2007) Old Yellow Enzymes, Highly Homologous FMN Oxidoreductases with Modulating Roles in Oxidative Stress and Programmed Cell Death in Yeast. J Biol Chem 282(49):36010-23