BEM4/YPL161C Summary Help

Standard Name BEM4
Systematic Name YPL161C
Alias ROM7
Feature Type ORF, Verified
Description Protein involved in establishment of cell polarity and bud emergence; interacts with the Rho1p small GTP-binding protein and with the Rho-type GTPase Cdc42p; involved in maintenance of proper telomere length (1, 2, 3)
Name Description Bud EMergence
Chromosomal Location
ChrXVI:246220 to 244319 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All BEM4 GO evidence and references
  View Computational GO annotations for BEM4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Mutant phenotypes All BEM4 Phenotype evidence and references
Classical genetics
conditional
null
Large-scale survey
null
overexpression
unspecified
Resources
interactions All BEM4 Interaction evidence and references
172 total interaction(s) for 127 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-Western: 1
  • PCA: 5
  • Reconstituted Complex: 1
  • Two-hybrid: 24
Genetic Interactions
  • Dosage Rescue: 8
  • Negative Genetic: 64
  • Positive Genetic: 11
  • Synthetic Growth Defect: 26
  • Synthetic Lethality: 26
  • Synthetic Rescue: 3
Resources
Expression Summary
histogram
Resources
Protein Information All BEM4 Protein evidence and references
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:246220 to 244319 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1902 246220..244319 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006082
References cited on this page View Complete Literature Guide for BEM4
1) Mack D, et al.  (1996) Identification of the bud emergence gene BEM4 and its interactions with rho-type GTPases in Saccharomyces cerevisiae. Mol Cell Biol 16(8):4387-95
2) Hirano H, et al.  (1996) ROM7/BEM4 encodes a novel protein that interacts with the Rho1p small GTP-binding protein in Saccharomyces cerevisiae. Mol Cell Biol 16(8):4396-403
3) Askree SH, et al.  (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63