KIP2/YPL155C Summary Help

Standard Name KIP2 1
Systematic Name YPL155C
Feature Type ORF, Verified
Description Kinesin-related motor protein involved in mitotic spindle positioning; stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle (2, 3)
Name Description KInesin related Protein 1
Chromosomal Location
ChrXVI:259336 to 257216 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All KIP2 GO evidence and references
  View Computational GO annotations for KIP2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
119 total interaction(s) for 48 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • Co-localization: 1
  • PCA: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 8

Genetic Interactions
  • Dosage Rescue: 4
  • Negative Genetic: 47
  • Phenotypic Enhancement: 2
  • Positive Genetic: 4
  • Synthetic Growth Defect: 17
  • Synthetic Lethality: 22
  • Synthetic Rescue: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 706
Molecular Weight (Da) 78,377
Isoelectric Point (pI) 10.2
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:259336 to 257216 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2121 259336..257216 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006076
References cited on this page View Complete Literature Guide for KIP2
1) Roof DM, et al.  (1992) Kinesin-related proteins required for assembly of the mitotic spindle. J Cell Biol 118(1):95-108
2) Cottingham FR and Hoyt MA  (1997) Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J Cell Biol 138(5):1041-53
3) Carvalho P, et al.  (2004) Cell cycle control of kinesin-mediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation. Dev Cell 6(6):815-29