SPO19/YPL130W Summary Help

Standard Name SPO19 1
Systematic Name YPL130W
Feature Type ORF, Verified
Description Meiosis-specific prospore protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; identified as a weak high-copy suppressor of the spo1-1 ts mutation; SPO19 has a paralog, YOR214C, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description SPOrulation 5
Chromosomal Location
ChrXVI:304387 to 305058 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SPO19 GO evidence and references
  View Computational GO annotations for SPO19
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
62 total interaction(s) for 56 unique genes/features.
Physical Interactions
  • PCA: 1

Genetic Interactions
  • Negative Genetic: 53
  • Phenotypic Suppression: 2
  • Positive Genetic: 4
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 223
Molecular Weight (Da) 24,988
Isoelectric Point (pI) 3.91
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:304387 to 305058 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..672 304387..305058 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006051
References cited on this page View Complete Literature Guide for SPO19
1) Primig M, et al.  (2000) The core meiotic transcriptome in budding yeasts. Nat Genet 26(4):415-23
2) Hamada K, et al.  (1999) Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins. J Bacteriol 181(13):3886-9
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Maier P, et al.  (2008) The SpoMBe pathway drives membrane bending necessary for cytokinesis and spore formation in yeast meiosis. EMBO J 27(18):2363-74
5) Esposito MS, et al.  (1970) Conditional mutants of meiosis in yeast. J Bacteriol 104(1):202-10