SPC29/YPL124W Summary

SPC29 BASIC INFORMATION

Standard Name	SPC29
Systematic Name	YPL124W
Alias	LPH3 , NIP29
Feature Type	ORF, Verified
Description	Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inner plaque component Spc110p; required for SPB duplication (1)
Name Description	Spindle Pole Component

GO Annotations	All SPC29 GO evidence and references
	View Computational GO annotations for SPC29
Molecular Function
Manually curated	structural constituent of cytoskeleton (IPI)
Biological Process
Manually curated	microtubule nucleation (IPI) spindle pole body duplication in nuclear envelope (IMP)
Cellular Component
Manually curated	central plaque of spindle pole body (IDA)

Mutant Phenotype	All SPC29 Phenotype details and references
Classical genetics
conditional	heat sensitivity: increased spindle morphology: abnormal
overexpression	budding: abnormal budding index: abnormal cell cycle progression: abnormal cell cycle progression in G2 phase: abnormal cell size: increased cellular morphology: abnormal
reduction of function	inviable
Large-scale survey
null	inviable
overexpression	vegetative growth: decreased

Interactions	SPC29 All interactions details and references
	44 total interaction(s) for 25 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-Western: 1 Biochemical Activity: 1 Co-localization: 2 Co-purification: 1 FRET: 6 Reconstituted Complex: 3 Two-hybrid: 17
Genetic Interactions	Dosage Lethality: 4 Dosage Rescue: 3 Synthetic Lethality: 4

Sequence Information

ChrXVI:316754 to 317515 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..762	316754..317515	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000006045

SPC29 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for SPC29

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SPC29]

1)	Elliott S, et al. (1999) Spc29p is a component of the Spc110p subcomplex and is essential for spindle pole body duplication. Proc Natl Acad Sci U S A 96(11):6205-10

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